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Cardiomyocytes from GRK2 heterozygous knockout mice (GRK2 exhibited augmented responses to SII in comparison to ANG, whereas those from GRK5 KO mice did not differ from those from WT mice.
Mathews, JA, Krishnamoorthy, N, Kasahara, DI, Hutchinson, J, Cho, Y, Brand, JD, Williams, AS, Wurmbrand, AP, Ribeiro, L, Cuttitta, F, Sunday, ME, Levy, BD, and Shore, SA. "Augmented Responses to Ozone in Obese Mice Require IL-17A and Gastrin-Releasing Peptide". American Journal of Respiratory Cell and Molecular Biology 58, no. 3 (March 2018): 341-351.
Moreover, low disease burden is known to be associated with augmented responses to anti-tumour vaccination [ 33].
The role of TNFα in the augmented responses to acute O3 observed in obese mice has not been established.
One of the studies in anesthetized rats reported augmented responses to deviant sounds, which the authors interpreted in terms of repetition rate.
TNFR2 is also required for the innate AHR that is observed in obese mice (Williams et al. 2012), but the role of TNFR2 in the augmented responses to O3 observed in obese mice is not established.
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The depressed group experienced a sharper baseline-cortisol decline between 08.00 and 11.00 h, and compared to control subjects they displayed an augmented response to the challenge.
The immune system is exquisitely poised to identify, respond to, and eradicate pathogens from the body, as well as to produce a more rapid and augmented response to a subsequent encounter with the pathogen.
Kit mutant animals are well-known for their augmented response to allergens.
This complex primes the patient's neutrophils for an augmented response to stimulation with zymosan.
Even very low doses of LPS elicit an augmented response to subsequent endotoxin challenge with a violent immune response [ 42 ].
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