Sentence examples for augmented proliferation of from inspiring English sources

Taken together with the finding of augmented proliferation of HM3KO cells after GDNF stimulation, our results suggest that GDNF-mediated c-RET kinase activation is associated with the pathogenesis of malignant melanoma.

IGF-1 treatment elevated pAkt, pGSK3β, and cyclin D1 levels resulting in augmented proliferation of HT-29 colon cancer cells.

Augmented proliferation of VSMCs in human atheroma has been associated with a decrease in Cav-1 expression [ 16].

These data therefore suggest that the ERα receptor is involved in the augmented proliferation of MCF-7 cells with impaired SNO homeostasis.

In addition, we have shown that augmented proliferation of progenitors in the OSVZ of the naturally gyrencephalic ferret led to the formation of extra cortical folds.

Similar to β-catenin gain-of-function, Notch1 deletion in embryos and ESCs leads to augmented proliferation of cardiac progenitors through increased Wnt/ β-catenin activity [ 33].

Multiple genetically engineered animal models demonstrated the importance of augmented proliferation on cyst development.

The hyperplastic lesions in the transgenic lungs showed increased number of epithelial cells positive for phosphorylated Histone H3 protein (pH 3), indicating augmented proliferation potentials of the epithelial cells in lungs of the transgenic animals (Fig. 3C).

Overexpression of C35 augmented proliferation, migration and tumourigenicity in ovarian cancer cell lines.

Accordingly, the increased expression of PAI-1 associated with diabetes can lead to augmented proliferation, diminished apoptosis, and hence accumulation of cells consistent with restenosis after PCI.

Thus, ROS are indeed genotoxic but, surprisingly, by virtue of their ability to mediate oncogene-driven augmented proliferation and aberrant DNA replication.