Sentence examples for augmented inflammation from inspiring English sources

ANG-2, stored in endothelial cell granules, may be rapidly released resulting in endothelial activation, augmented inflammation, loosening of endothelial cell junctional complexes, and upregulation of cerebral endothelial adhesion molecules such as ICAM-1 to which parasitised erythrocytes adhere.

In summary, this set of experiments yielded results similar to those observed in the first set of experiments in which mechanical ventilation augmented inflammation and lung permeability in the setting of TLR3 activation.

For that reason, a panel of chemokine transcripts (or chemokine proteins) might be predicted to provide a measure of a broader complement of molecular influences that result in flares of disease activity or augmented inflammation in a target organ.

Yin and colleagues independently generated a Grn knockout mouse model from which they discovered that Pgrn loss augmented inflammation, leading to an increase in the production of proinflammatory cytokines [ 71].

Animal experiments of apoA-I deficient mice have shown that an accelerated atherosclerotic process is mechanistically attributed to impaired reverse cholesterol transport, reduced PON activity, and augmented inflammation [ 10], whereas peritoneal injection of apoA-I mimetic peptide effectively prevents early atherogenesis, accompanied with increment of PON activity [ 11].

Yet, this augmented inflammation was associated with striking resistance to host mortality (0% vs 90% survival, p = 0.0001) and reduced viral titers (p = 0.004).

Our findings provide evidence for a mechanism by which PAF augments inflammation in the intestinal epithelium through abnormal TLR4 upregulation, thereby contributing to the intestinal injury of NEC.

Therefore, thrombin may activate PAR1 receptors in the urothelium to elicit MIF release from urothelial cells and thus continue and/or augment inflammation in the bladder.

Besides hyperglycemia, also uremia and high osmolarity seem to augment inflammation.

The formation of amyloid plaques also activates glial cells to augment inflammation in the brain.

Therefore, decreased sRAGE levels may enhance full-length RAGE signaling and thereby augment inflammation.