Exact(2)
This correlated with augmented expressions of cell cycle-related genes and abnormal activation of Rac1/c-jun N-terminal kinase (JNK).
Taken together, macrophage accumulation in the kidney and the augmented expressions of these FABPs in macrophages would aggravate local inflammation and contribute to the progression of nephropathy in diabetes.
Similar(58)
Since we notice an augmented expression of cofilin in cells expressing N, it will be interesting to see if the N-induced effects on cofilin are also associated with altered phosphorylation of the protein and if effects of N and glycoprotein complex are in reciprocal directions.
DCs treated with MAP MDH displayed characteristics of the activated and mature immune status, with augmented expression of cell surface molecules and pro-inflammatory cytokines, including TNF-α, IL-1β, IL-6, and IL-12p70, but not IL-10, along with a dose-dependent decrease in the antigen uptake capacity.
ILK knockdown in MC3T3-E1 osteoblast-like cells reduced phosphorylation of its downstream target glycogen synthase kinase 3β (GSK3β), which led to cytoplasmic retention of αNAC and increased mineralization with augmented expression of the osteoblastic differentiation markers, pro-α1(I) collagen (col1A1), Bone Sialoprotein (Bsp) and Osteocalcin (Ocn).
PARM-1 silencing also repressed expression of PERK and ATF6, and augmented expression of CHOP without affecting IRE-1 expression and JNK and Caspase-12 activation.
Our findings indicate that augmented expression of BteA protein in B. pertussis circulating strains could play a key role in the type shift.
As expected, feeding mice a high-fat diet lead to augmented expression of UCP1 in both iBAT and iWAT in vehicle-treated mice (Figure 7E).
We observed that prolonged falegllin treatment impaired NF-κB activation, muted pro-inflammatory cytokine production, and augmented expression of antimicrobial molecules [30].
Again, WNV epitope specificity revealed itself as SVG9 but not SLF9 specific T cells exhibited an augmented expression of CD107a (Figure 7).
This type-dependent expression is due to an insertion of IS481 in B. pertussis clinical strains, suggesting that augmented expression of BteA protein might play a key role in the type shift of B. pertussis.
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