Sentence examples for augmented downstream from inspiring English sources

Hence, increased tyrosine kinase signaling induced by dysregulated RTKs in BTBC can lead to increased SHP2 activity and augmented downstream signaling.

Given the risk of occlusion, some surgeons may choose to place arterial catheters in the distal extremity to augment downstream limb perfusion.

In the myocyte, insulin enhances MGU by driving GLUT-4 translocation to the cell membrane via insulin receptor substrate (IRS -1, and by augmentIRS -1wnstreandanabylic paugmenting7].

However, little is known as to how modulating the spatial presentation of a ligand augments downstream immune responses.

EGF is also capable of activating additional PI3-K pools and, thereby augments the downstream signalling of insulin in insulin-resistant states like T2D [14].

Treatment of K1003A-10A cells with insulin or IGF-I did not augment phosphorylation of downstream signaling pathways; however, there was still some detectable phosphorylation of Akt and ERK after insulin and IGF-I stimulation, most likely resulting from the mixed population of infected cells.

TF/FVIIa did not affect basal beta cell death but, independently of downstream coagulation activity, augmented beta cell death in response to cytokines.

First, a functional non-canonical pathway downstream of LTβR augmented the RelA activity induced by pathogen sensing TLR4 in otherwise hypo-responsive MSIE colon epithelial cell-line.

NF-AT was severely reduced and AP-1 was slightly diminished in AIP downregulated Jurkat T cells, highlighting that AIP augments TCR/CD28 downstream pathways that contribute to optimal IL-2 induction.

Downstream, FABP3 and ACADl/ACADm transcripts were augmented by HF.

Transduction with Ad5/p53 however suppressed production of replication-competent AdF35 progenies, but the combination augmented Ad5/p53-mediated p53 expression levels and the downstream pathways.