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Immunohistochemical staining with mouse macrophage-specific F4/80 antibodies showed that mouse macrophages were much more abundant in MCF7S1 + HMF3s tumours compared with MCF7S1 tumours (Fig. 6A, lower panel), suggesting that augmented development of mouse-derived stroma produces soluble factors that support oestrogen-independent growth of MCF7S1 tumour cells.
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Many studies have demonstrated that chronic AngII (angiotensin II) infusion into hypercholesterolaemic mice augments development of atherosclerosis and promotes formation of AAAs (abdominal aortic aneurysms) [ 1– 8].
Thirdly, this study revealed that although the types of questions mattered in the production of sound and strong argument, it was how these questions were organized into a visible schema that further augmented the development of quality arguments.
The protective effect of thalidomide was augmented in development phase when co-administration with NOS inhibitors like L-NAME (non- selective NOS inhibitor; 2 mg/kg) or aminoguanidine (selective inducible NOS inhibitor; 50 mg/kg).
Following agile methodology, most specifications were refined and augmented during development, informed by process mapping, feedback from the informatics specialists and usability testing.
Interpretation of the trend and range of SpO2 values observed in infants is currently limited by a lack of reference ranges using current devices, and may be augmented by development of cumulative frequency (CF) reference-curves.
Similar effects on mammosphere formation were found by Klopp et al [ 93], who found reduced E-cadherin expression in normal and breast-cancer epithelial cells, and the MSCs augmented tumour development when co-injected into mice.
Here, Scuoppo and co-workers demonstrated that the shRNA-mediated reduction of eIF5A expression, or decreased hypusine modification through knockdown of DHS, augmented lymphoma development in the Eμ-myc mouse model.
It is worth to note that both I and PL rats had augmented alveolar development compared to Null rats, but the level of differentiation in terms of β-casein expression is higher in PL rats, supporting a role for the extent of differentiation more than the alveolar development in the protective effect of PL.
Only one report has shown that prior P. gingivalis oral infection augments development of collagen antibody-induced arthritis in mice [ 27].
Moreover, BMP4 is a target-derived cue that augments development of somatosensory neurons in the trigeminal ganglia (TG) and dorsal root ganglia (DRG).
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