Sentence examples for augmented cell proliferation from inspiring English sources

Consequently, transient transfection of the low aggressive phenotype and low-level expression of ACSL4 cell line, MCF-7, with the full length human ACSL4 cDNA resulted in increased aggressiveness of the cells manifested as augmented cell proliferation, invasion and migration.

These results suggested that downregulation of NDUFB6 is not implicated in invasion or migration, but implicated in augmented cell proliferation.

The expression of ERα is thus required for the augmented cell proliferation under moderate conditions of nitrosative stress in breast tumor cells.

Both AGR2-mediated inhibition of p53 tumor suppressor activity and AGR2-associated expression of genes that regulate cell growth and survival may directly contribute to the tumor-promoting activity of AGR2 through augmented cell proliferation and survival.

It may contribute to BC pathogenesis by augmenting cell proliferation via stimulation of cell cycle progression and by increasing the expression of genes involved in angiogenesis and metastasis.

This is relevant because B-myb is a transcription factor that can regulate the expression of genes that augment cell proliferation, suppress tumorgenesis and inhibit cellular senescence [ 22].

In addition, OPN-c is capable of augmenting cell proliferation and invasion of the ovarian cancer cell line OvCar-3 and this was found to be mediated through PI3K signalling (Tilli et al, 2011).

In vitro functional studies indicated that miR-143 and miR-145 appear to function in opposing manners to either inhibit or augment cell proliferation in a metastatic CRC model.

A recent global miRNA expression analysis indicated that miR-143 and miR-145 also appear to function in opposing manners to either inhibit or augment cell proliferation in a metastatic CRC cell model [ 12]. miR-126, which is also frequently lost in colon cancers, can suppress the growth of neoplastic cells by targeting phosphatidylinositol 3-kinase signaling [ 13].

Thus, DDX3 has diverse functions in a variety of cell types, in breast cancer cells DDX3 augments cell proliferation whereas in hepatocellular carcinoma cells it promotes growth arrest and tumor suppressing activities.

Collectively, our data demonstrates that Akt2 augments cell proliferation by facilitating cell cycle progression through the upregulation of the cell cycle engine, and protects a cell from pathological autophagy by modulating mitochondrial homeostasis.