Prior studies suggest the usefulness of intralesional steroid injection into benign esophageal strictures for augmentation of the effects of endoscopic dilatation [ 9, 10].
26– 28 Since leucine activation of SIRT1 results in significant augmentation of the effects of other compounds that converge on this signaling pathway, 10– 13 we considered the potential for leucine to amplify the effects of PDE5-inhibitors.
The mesolimbic dopamine system is considered to play a pivotal role in the locomotor activation produced by psychostimulants and in the augmentation of this effect observed upon repeated drug administration, a process denominated behavioral sensitization.
The nucleus accumbens is critically involved in the locomotor activation produced by psychostimulants and in the augmentation of this effect observed upon repeated drug administration (i.e. behavioral sensitization), although there is not a general consensus as to whether the nucleus accumbens-core or the nucleus accumbens-shell is preferentially involved in such alterations.
Furthermore, methods of augmentation of the EPR effect are described, that result in better tumor delivery and improved therapeutic effect, where nitroglycerin, angiotensin I-converting enzyme (ACE) inhibitor, or angiotensin II-induced hypertension are employed.
Activation of NF‐kB dependent cytokine production and glial activity increases with age in the hypothalamus, and augmentation of this effect, either genetically or by viral‐mediated gene delivery, can shorten mouse lifespan (Zhang et al., 2013).
The NP size-dependent SHC is resulted from an augmentation of the nanolayer effect as particle size reduces.
Thus, one observes a decreased SHC as particle size reduces, and particle concentration increases because of the augmentation of the nanolayer effect.
The former is caused solely by the gravity effect, whereas the latter is caused by the superposition of the coagulation and the gravity effects, i.e., the amplification and augmentation of the gravity effects of the aggregated particles due to coagulation.
Pretreatment with MPP did not lead to blockade or augmentation of the inhibitory effects of ICI on PRL release.
