Sentence examples for augmentation of proinflammatory from inspiring English sources
Augmentation of proinflammatory cytokine and autoantibody production in arthropathic Tax transgenic mice.
We therefore expected that PS2 knockdown microglia may demonstrate a similar augmentation of proinflammatory cytokines as was observed in response to pharmacological γ-secretase inhibition.
We did not identify any significant SNPs in the HLA region in our GWAS, suggesting that augmentation of proinflammatory cytokine signaling through ERAP1 is more likely involved in KD.
Interestingly, mutations of CIAS1 cause several autoimmune inflammatory syndromes [ 39, 40] and its downregulation in SAA patients may contribute to the immunpathology of AA by augmentation of proinflammatory signals.
Higher levels of proinflammatory CSF IFNγ were associated with more rapid rates of fungal clearance during treatment [ 17, 19] and lower fungal burdens at presentation, demonstrating the importance of IFN-γ in the protective immune response, and reinforcing the rationale for augmentation of proinflammatory responses with IFN-γ immunotherapy as a therapeutic approach [ 16].
Moreover, heparin acts as a potent anti-inflammatory agent that inhibits enzymes and cytotoxic mediators, released from proinflammatory cells, responsible for augmentation of inflammation, such as elastase, cathepsin G, eosinophil peroxidase, eosinophil cationic protein, major basic protein, interleukin-8, and stromal-derived factor-1 [ 53, 54].
To review the concept of proinflammatory cytokines.
These data demonstrate differential regulation of proinflammatory cytokines by stress.
Preliminary genic expression studies instead documented the activation of proinflammatory genes during the CH attack [163].
The purpose of this study was to determine whether the proinflammatory effect of GC arise from epigenetic pattern modifications in the regulatory regions of proinflammatory genes.
Repeated endotoxin exposures induce periods of endotoxin tolerance, characterized by diminished proinflammatory responses to lipopolysaccharide (LPS) and modulated production of proinflammatory cytokines.
