They base this on the observation that models in which the effects of activators can simply be added to those of repressors are sufficient to produce the stripe 2 pattern, and there is no need to assume that activators bound to adjacent sites cooperate with each other to augment their activities.
Can we augment their activities and live even longer?
Inflammatory mediators called cytokines produced by T lymphocytes and macrophages act on specific sodium transporters in the kidney, augmenting their activity or expression, with consequent expansion of intravascular fluid volume and cardiac output.
Phosphorylation of ER-α coregulatory proteins augments their activity on ER-α dependent transcription, alters nuclear localization, affects their binding to ER-α, and enhances their ability to recruit other transcriptional coregulators [ 56, 57, 61].
If the Nazi marchers and racist hate mongers "augmented" their activities with videos of graphic violence against Jews and blacks, would The New York Times rush to their defense on constitutional grounds?
Preceding studies exemplify that each of the three components of TD has their proven medicinal value individually and the amalgamation of these is likely to augment their antioxidant activity.
Undoubtedly, detailed knowledge of such factors would be instrumental not only for the identification of suitable biomarkers for risk-stratified treatment decision-making and response prediction but also for the development of rational combination therapies aimed to overcome relative resistance to BiTE antibody constructs and augment their clinical activity.
As a result of the 1993 1994 survey of the GL states, the health departments of these states chose as a priority to augment their ongoing activities with the development of outreach materials aimed at young women and children.
One of these groups also performed a series of experiments examining how ATRA affected the expansion and function of natural Tregs and concluded that ATRA augmented their suppressive activity and should therefore be considered for use in Treg-based therapy.
Meis1, Mrg1 and other members of the TALE family serve as Hox cofactors by altering HOX-DNA binding specificity, to increase DNA binding affinity thereby augmenting their transcriptional activity [131].
