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However, we hypothesize that by altering construct properties, such as cell density and polymer concentration, we can augment the expression of endogenous IGF-1 in chondrocytes.
CD28 co-stimulation can also augment the expression of Bcl-xL, a key cell survival molecule that prevents the induction of apoptosis [16].
MSCs inhibit TNF-α secretion, augment the expression of anti-inflammatory cytokines, and promote IL-6 secretion.
Double knockdown of DKC1 and XPC appeared to further augment the expression of Cdx2 but not Fgf5.
Glucocorticoids can augment the expression of HIF1α-dependent HIF1α-dependentect interaction with HIF-1α [ 37].
Insulin was shown to directly augment the expression of PAI-1 in a hepatocyte cell line, HepG2 (8).
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Noman AS et al [ 21] reported that LPS significantly augmented the expression of RIZ1 and the augmentation was mediated by the activation of nuclear factor (NF -κB aNF -κB.
Additionally, sitagliptin therapy augmented the expression of GLP-1R in renal parenchyma, and the expression was particularly prominent in the glomeruli (Figure 4A 4D).
This study further tested whether sitagliptin therapy augmented the expression of EPCs and angiogenesis factors in kidney parenchyma in the setting of acute IR injury.
The ACE inhibitors also augmented the expression of HGF in the presence of bradykinin in human aortic endothelial cells in culture (HAECs).
Furtherfore, IL-15 augmented the expression of cytotoxic effector molecules (TRAIL and Perforin) and the phosphorylation of STAT1 and ERK1/2, which may also contribute the NK lysis.
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