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This chapter outlines the challenges associated with effective drug and gene delivery to tumors, and strategic approaches to augment the efficacy of anticancer agents by utilizing multifunctional nanosystems.
While yoga therapy is not a cure, it can improve the quality of life, and may augment the efficacy of clinical treatment.
To our knowledge, this is the first report that long-term weakening of feedforward connections can augment the efficacy of Schaffer collateral-mediated glutamatergic transmission (see Figure S3 for model).
IL-12 has been shown to augment the efficacy of cancer vaccines.
We hypothesised that altering TAM phenotype would augment the efficacy of immunotherapy.
The addition of adjuvant to vaccines is mandatory to augment the efficacy of immunization.
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In the present case, bicarbonate infusion prior to ILE injection likely served to increase the percentage of circulating amitriptyline in the un-ionised state and therefore amenable to lipid sequestration, potentially augmenting the efficacy of the 'lipid sink'.
The intention of this modification is primarily to utilize the overexpression of glucose transporters (GLUT) in tumour cells for increased cellular uptake of the cytotoxic agents into cancer cells [93], thereby augmenting the efficacy of this alkylating drug candidate.
This "one-two punch" directs immune responses against tumor cells while lowering the threshold for macrophage activation, thereby providing a universal method for augmenting the efficacy of therapeutic anticancer antibodies.
Our results also show that, under gastric conditions, ASP augments the efficacy of gluten-detoxifying endoproteases such as the glutamine specific EP-B2 from barley [6].
3-aminobenzamide augmented the efficacy of TMZ regardless of MMR status [23], [24].
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