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This interpretation raises the specter that naive attempts at lethal mutagenesis may augment adaptation rather than retard it.
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Concomitantly, the mice manifested augmented respiratory adaptation and greater survival rate following AH.
In contrast, in elderly individuals (60 80 years), where the antioxidant status is expected to be lower, we tested the hypothesis that supplementation with vitamin C and vitamin E would augment the adaptations to strength training.
18 Training, particularly high-intensity training, in hypoxia has been shown to augment peripheral adaptations to training, such as improved oxidative enzyme activity, 19 length density and mitochondrial volume density, 20 22 as well as increased expression of hypoxia inducible factor-1α and downstream genes related to oxygen transport and utilisation.
Elevated cortisol concentrations have been reported as a primary hormonal factor augmenting exercise adaptations from high-intensity exercise, as well as impacting rates of lipolysis [20].
Thus, there is an important need to identify adjuvant therapies capable of augmenting mitochondrial adaptations to exercise (e.g. improved mitochondrial respiration, muscle mitochondria biogenesis) among older adults.
In recent years hormonal stimulation to augment remnant bowel adaptation has been suggested, with glucagon-like peptide 2 (GLP-2)—a peptide which is secreted from the intestinal L-cells following ingestion of a meal as a key factor.
We argue that similarity must be augmented by deeper, adaptation knowledge about whether a case can be easily modified to fit a target problem.
Repeated sprint training has been shown to improve RSA, we hypothesised that hypoxia would augment these training adaptations.
Specifically, we here compare three models of rivalry (Fig. 1), which serve as prototypes for broad classes of rivalry models: first, networks of self-exciting units with mutual inhibition (model 1); second, the same network augmented with an adaptation mechanism in the excitatory units (model 2); third, our new approach, two coupled networks that implicitly form a memory state (model 3).
We hypothesized that vitamin E (vit E) deficiency, which will increase oxidative stress, would augment the training-induced adaptation of antioxidant enzymes.
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