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Separate psychometric functions were calculated for congruent and incongruent trials for each participant by fitting the ratios of "auditory right" responses plotted against spatial displacement (measured in degrees of visual angle, with negative values indicating that the auditory stimulus was placed to the left of the visual one) with a cumulative Gaussian distribution [29](see Figure 3B).
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Group x condition interaction effects were observed in left primary auditory cortex, right middle temporal cortex, and in default-mode areas within posterior parietal cortex.
Previously, we found that dorsolateral prefrontal, posterior parietal, left primary auditory, and right middle temporal cortices all showed increased activation during the noisy relative to the quiet listening conditions within the younger adults [48].
The NBS method analysis showed increased connections between auditory system (right superior temporal gyrus) and visual system and decreased connections within the visual network, including the bilateral calcarine sulcus, the bilateral cuneus, and the bilateral lingual gyri.
In summary, the regions that we associate with audiomotor expertise are associated with fine-grained auditory analysis (right pSTS), speech categorization (left pSTS), audiomotor integration (left PT), and the integration of sound sequences over long timescales (left aSTG).
A statistical analysis of the data (within-subjects ANOVA) confirmed that there was no significant difference between visual targets (left panel) and auditory targets (right panel), F 1, 27) = 0.54, p =.48, nor was there an effect of nontarget stimulus timing, F 3, 27) = 1.50, p =.24.
For problems presented with Arabic numerals we found significantly positive correlations between the self-reported use of verbalization and activation in ROIs implicated in auditory processing, the right and left Heschl's gyrus (right: r =.367, p =.028; left: r =.357, p =.033), and the left Rolandic Operculum (r =.374, p =.025).
To test this, we stratified trials of both conditions with respect to prestimulus alpha power for the right auditory cortex, leaving no significant differences in prestimulus auditory alpha power between conditions.
Therefore, we cannot rule out that MEG-MRS associations for the right auditory cortex differ from those reported here for the left auditory cortex.
Simultaneously, the enhanced coupling of right auditory regions to a task-relevant central hub of the network (left auditory cortex) ensures the propagation of the stimulus presentation to higher order processing regions of the brain.
In addition, we were able to show that significant network modulations of the right auditory cortex, which were mainly characterized by a decoupling from non-auditory brain regions, persist after controlling for significant differences in prestimulus alpha power between conditions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com