Your English writing platform
Discover LudwigExact(6)
Our group described a recurrence after 3 months probably due to the atypical site of localization or to the histologic and immunohistochemical characteristics.
It is probable that these mutations facilitate binding of DRV to this atypical site.
Superposition of the two monomers reveals that three side chains of the wild-type enzyme lie close to DRV in this atypical site.
The question of whether DRV might bind at this atypical site in wild-type enzyme can be addressed by structural comparison.
However, rotated conformers of the side chains of Ile54, Val82, and Ile84 could allow the possible binding of DRV in the atypical site.
This contrasts with previous studies, which have suggested heavy N-glycosylation of up to 10 kDa, possibly at one site in the 24 kDa moiety (Todorov et al, 1997), but is consistent with the observation that neither site represents a typical consensus N-glycosylation sequence, although N32 has the characteristics of an atypical site (Welply et al, 1983; Sato et al, 2000).
Similar(54)
Some patients suspected for recurrent aphthoid stomatitis develop lesions in atypical sites - mainly in the larynx - concurrently to the ones found in the oral mucosa.
Patients with VL and HIV co-infection usually have a CD4 count less than 200 cells/μl, may have involvement of atypical sites, like the eye, and are prone to a relapsing VL course despite appropriate treatment [9],[9]].
The GNA11Q209L mice recapitulated human Gq-associated melanomas, and they developed pigmented neoplastic lesions from melanocytes of the skin and non-cutaneous organs, including the eye and leptomeninges, as well as at atypical sites, including the lymph nodes and lungs.
The described cases of atypical sites include the pleura, pericardium, kidney, adrenal gland and the brain.
KS in these atypical sites may prove difficult to diagnose, resulting in patient mismanagement.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com