However, we emphasize that our findings are derived from a specialized and somewhat atypical clinical research environment; given the wide variability in the design and conduct of clinical trials, our results may not be generalizable to other research venues and should be viewed as hypothesis-generating only.
Across a range of disorders within both typical and atypical development, research has suggested that individual differences in early AC/WM, along with the related domain of processing speed, correlate with subsequent learning abilities in a range of different domains.
Likewise, the MSI scheme incorporates a measure for fear avoidance behaviour, but the developers/experts state this population subtype is atypical within their research and clinical setting (Sahrmann and Van Dillen, survey response).
We find that search scope, search depth, and atypical connections between different research domains significantly increase a paper's impact, even when controlling for the experience and prior publishing success of the author(s).
Modeling ovarian cancer however is challenging as a result of the genetic heterogeneity of the malignancy, the diverse pathology, the limited availability of human tissue for research, the atypical mechanisms of metastasis, and because the origin is unclear.
In sum, previous research suggested atypical patterns in processing of threatening information among maltreated individuals.
Algorithms using clinical features could be used for diagnosis with laboratory confirmation as a backup for atypical presentations and further research.
Another question that can be addressed in research with atypical populations is that of whether some individuals may benefit more from training than others (cf. Söderqvist et al., 2012).
It is also worth noting that much of the research on atypical antipsychotics has been carried out in samples with below-average IQ; there are few high-quality data in samples with average IQ.
The drawbacks of experiments are uncertainties in the scale-up from small, simple environments to larger and more complex systems; the concern that taxons with short life cycles used for experimental research are atypical of those of harvested species; and the difficulty of adequately simulating selection due to fishing.
