In the future, it will be of great interest to examine C9ORF72 in two-generation families with bipolar disorder with or without dementia, in those with atypical cognitive and personality profiles, and in families with other neuropsychiatric syndromes demonstrating clinical anticipation.
Here we show that unusual architecture in the microstructure of the human brain is related to atypical mental projections of personality and social structure onto things that are neither living nor animate.
There is also a growing acceptance that subtle autism-like traits, such as atypical communication and aloof personality style, more commonly cluster in the nonautistic family members of individuals with autism than in the general population (Murphy 2000).
Personally, I found I could tackle stressful situations in a non-reactive manner (very atypical of my type-A personality).
Soon after Mr. Geoghan's reinstatement, the documents show, Bishop Banks wrote to doctors at the treatment center, who had written that Mr. Geoghan had "atypical pedophilia, in remission" and "mixed personality disorder with obsessive-compulsive, histrionic and narcissistic features".
Therefore, there is need for further research to explore the effectiveness of clozapine or other atypical antipsychotics in this subgroup of personality disorder patients.
Atypical drugs are administered also in case of personality disorders (44%; 42% typical) or affective psychoses/depressive episode-status (45%; 25% typical).
Background: Few treatment studies of schizotypal personality disorder (SPD) have investigated the new, atypical antipsychotic drugs.
This lack of association contrasts with Adolphs et al. [32] who found parents of ASD children with an aloof personality type were more impaired, and exhibited more atypical processing of emotional faces than non-aloof ASD parents.
Dementia in these families was often atypical but most resembled FTD [ 27], with changes in personality, behaviour and insight, together with extrapyramidal motor features.
Many contextual influences are difficult to control: the patient's characteristics and personality, the demographics and presentation (both typical and atypical) of the disease process itself, the knowledge, experience, expertise, personality and other characteristics of the physician, and the ambient conditions under which the decision will be made.
