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The variable change in restrictiveness can take three values [−1, 0, +1] and the basis for deciding whether a policy introduced a more or less restrictive change was whether it extended or restricted the rights attributed to the targeted migrant group.
We confirmed that the increase in abnormal metaphase could be attributed to the targeted repression of CRMP4 by rescuing the phenotype with an siRNA-resistant wild type rat CRMP4 construct (L-CRMP4-WT-V5) (Fig. 2C).
Therefore gene expression profiles can be precisely attributed to the targeted microdissected cells.
Thus, the observed reduction in CCR5 expression and inhibition of HIV infection with EGS C1 is primarily attributed to the targeted cleavage by RNase P as opposed to the antisense effect or other nonspecific effects of the EGSs.
In part, this can be attributed to the targeted disruption of gcd, since more than ten transfers had been required for strain S12xylAB2 to acquire a gcd negative phenotype.
In order to validate that the observed phenotype could be attributed to the targeted deletion, complementing plasmids were constructed by inserting appropriate genes downstream to the lac promoter encoded in pBBR1MCS-5.
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The health benefits of phytochemicals are often attributed to the targeting of reactive oxygen species (ROS).
The enhanced inhibition rate accomplished with the combinatorial gene expression cassette can most likely be attributed to the targeting of 2 different steps in adenoviral DNA synthesis.
The inhibitory effect of PKI166 on prostate cancer bone metastasis has also been attributed to the targeting of both tumour cells and endothelial cells (Kim et al, 2003).
The tumour necrosis was at least as good as that of HpD, and this therapeutic response may be attributed to the targeting of specific 'photopotent' subcellular sites.
In HIV infection, the protective effects associated with class I alleles, for example HLA-B*27, have been attributed to the targeting of epitopes which lie in structurally or functionally constrained regions.
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