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Essential revisions: 1) There are a number of cases where the phenotypes/gene expression changes attributed to altering MP and SYD/BRM could be due to very indirect effects.
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Lithiation-induced stresses during lithiation are attributed to alter the driving force of lithiation and thus result in the observed slowing of reaction front.
For instance, OA osteoblasts show blunted cAMP synthesis in response to human parathyroid hormone and PGE2 in contrast to findings in normal cells, a result that is not attributed to altered adenylate cyclase activity (Hilal et al. 1998).
Third, perhaps the main defects in the Hippo signalling core can be attributed to altered post-translational modifications (PTMs) at the protein level, in which case genomic data cannot be used.
Likewise, changes in gene expression observed in the Δstp1 and Δstk1 strains could also be attributed to altered HU function.
The recruitment of regions that typically respond to visual stimuli has been attributed to altered connectivity between primary visual areas and brain regions subserving other sensory modalities [70].
This outcome was attributed to altered solubility and a modified lignin structure with low local molecular mobility, presumably due to condensation reactions.
The slower movements of the NS group may be attributed to altered motor control due to pain, see e.g., [ 33- 35] and/or mechanical dysfunction.
GERD development can be attributed to altered gastric emptying, decreased gastric compliance resulting in increased intragastric pressure, as well as the anatomical changes in the angle of His.
This suggests that the difference in glucose metabolism observed in these regions may not be attributed to altered 5-HT synthesis.
These findings suggest that the different biological behaviour of the cell lines cannot be attributed to altered size and charge density of their GAG chains.
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