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Furthermore, decreased l-alanine formation was attributed to a mutation in the global regulator GlxR.
The remaining 10% are familial cases among which 20% can be attributed to a mutation in the superoxide dismutase (SOD1) gene.
Suffice to say, there is very little question that the muscularity of the Piedmontese breed can be largely attributed to a mutation in the MSTN coding sequence.
The symptoms are attributed to a mutation in the gene encoding the α1(I) chain of type I collagen (COL1A1) [ 34].
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The generation of various Cry toxin-resistant insect strains has been attributed to a mutation or deletion in BtR [ 5– 8].
The disorder is inherited in an X-linked dominant manner, and is attributed to a missense mutation in the MED12 gene.
Approximately 20-25% of familial breast cancers can be attributed to a germline mutation in BRCA1 or BRCA2[ 7, 20].
ESTR mutation frequencies in the germline and somatic tissues of male and female mice irradiated at 12 days of gestation remained highly elevated during adulthood, which was mainly attributed to a significant increase in the frequency of singleton mutations.
But the absence of agr expression in the svrA mutant was later attributed to a frame-shift mutation in agrC [32].
Furthermore, it is often attributed to a genetic predisposition with germline mutations in the BRCA1/2 genes [ 19– 22].
In the fifth family, the disease manifestation has been attributed to a compound heterozygote DES mutation (p.Ala360Pro/p.Asn393Ile [ 58]) (Table 1).
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