Instead of attributing significance to potentially strange results, it is the business of science to try and prove them wrong before we blindly move forward.
"The way human beings attribute significance to objects hasn't changed since we began having objects," he said, fishing around in his box.
To attribute significance to any of the p-values calculated in the ANOVA and pairwise contrasts, we used a 10% False Discovery Rate (FDR, Benjamini-Hochberg, step-up) cutoff for analysis of the data [ 37].
The origin for choosing ' P < 0.05' as a standard was traced back to Fisher in 1925 [ 4], although he was himself prepared to be flexible when attributing significance and fortitude with regard to actual P-values.
A comparison was also made to a more traditional statistical testing method, the F-test, and Bayesian analysis was found to perform more conclusively and to be capable of attributing significance to more subtle differences in growth rate.
While SIEVE analysis fails to attribute significance (p < 0.05) to PCP-induced alterations in the overt concentration of many metabolites in this cluster, GSVD analysis reveals that the relationship between these metabolites is significantly altered by PCP treatment (p < 0.001), highlighting the specific metabolic pathways that may be disrupted in the PFC of PCP-treated animals.
While SIEVE analysis fails to attribute significance (p < 0.05) to PCP-induced alterations in the overt concentration of many metabolites for many metabolites in this cluster, the PCP/Control ratio suggests that the levels of many of these metabolites are markedly altered by PCP-treatment.
As in previous and subsequent similar episodes, Adi Da attributed special significance to it, calling it his "Divine Emergence".
Concomitantly, others have attributed immunological significance to CelTOS by demonstrating that CelTOS-specific peptides can stimulate the PBMC's isolated from volunteers immunized with irradiated sporozoites, a highly effective vaccine inducing sterile protection, to produce antigen-specific IFN-γ responses, emphasizing the potential immunological impact of this antigen [6].
We attributed statistical significance to p values ≤ 0.05 in all comparisons.
