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Therefore, in addition to contraction, expression of PCGs is a major attribute of muscle throughout the planarian body wall.
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We sought to explore the attributes of muscle that might make it well suited to act as a source of positional information by analyzing the planarian muscle transcriptome.
Reduced myoblast proliferation is not commonly linked to muscular dystrophy, which is more classically attributed to death of muscle fibers, such as in Duchenne muscular dystrophy [45], or a combination of enhanced fiber degeneration and defective differentiation kinetics such as in Lmna−/− mouse models [39], [46].
However, some exceptions were identified: expression of SOX8 previously attributed to muscle satellite cells was correlated with angiogenesis.
These impairments were attributed to the loss of muscle bulk, proximal muscle weakness, and fatigue [ 49].
This better recovery is attributed to a lowering of muscle lactate.
Thus, one may speculate that at least partially the differences may be attributed to various methods of muscle mass measurement.
Previous work showed that muscle wasting in animal models of cancer cachexia was diminished by β-adrenergic agonists (e.g., formoterol and clenbuterol), with a possible mechanism of action attributed to the inhibition of muscle proteolysis [ 18, 19].
They have been attributed to muscle membrane dysfunction.
One study on brace treatment attributed pain relief to reduction of muscle cocontractions [ 20].
This extra reduction in EELV (34% versus 25%) is probably due to loss of muscle tension attributed to the use of sedation in our ICU patients.
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