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Then we used the Affymetrix Copy Number Analysis Tool (CNAT [ 39]) to attribute a copy number (CN) state to each SNP of all CoLaus individuals with the following encoding: 0 for homozygous deletion, 1 for hemizygous deletion, 2 for copy neutral, 3 for simple gain and 4 for multiple gains.
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Subsequently we used the OverUnder algorithm [16] to correct the hybridization log ratios for polyploidy and to attribute a continuous copy number value to each SNP.
Correction: October 23, 2003, Thursday An article on Tuesday about the opening of the Walt Disney Concert Hall in Los Angeles mistakenly attributed a comment in some copies about the hall's symbolism.
Taxonerator is written in Groovy, runs under Java 1.5 and 1.6, and requires a live internet connection, a preformatted database of taxonomically attributed reference sequences, a copy of the freely available text dump of the NCBI taxonomy hierarchy, and the BLAST suite of programs.
The article and, in some copies, a picture caption also erroneously attributed a distinction to the A's stadium.
Tristran was attributed a variety of arms.
In a subset of these cases, the observed underexpression can be attributed to copy number loss.
The name is attributed to copy writer Terry Hill, whose first choice "The Dream Team" was rejected.
The genome size difference was attributed to copy number variation of coding and non-coding sequences.
Analysis of Log R ratios and B allele frequencies confirmed that the rHH regions are not attributed to copy number deletions.
In breast cancer, it has been reported that 44%to62%2% of highly amplified genes were over-expressed [ 31, 32] and at least 12% of the total variation in gene expression was directly attributed to copy number aberrations [ 33].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com