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However, the supra-additive induction of apoptosis by UCN-01 or STP in combination with TSA may also be attributable to their function as negative modulators of Akt and MEK/ERK1/2 activation via inhibition of PDK1 (Sato et al, 2002), in addition to being PKC inhibitors.
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The extensive divergence in the VMA homing endonucleases is attributable to their loss of function.
In fact, it has been recently shown that, while both prelamin A and progerin exhibited increased binding capacity to histone H3 peptide in comparison with lamin A, probably attributable to their gain of function, they showed differences in binding to H3K27 peptide [ 10].
Although these same three "front entrance" built-environment features were associated with higher levels of social support at baseline, which sequentially were associated with psychological distress and physical functioning, almost all of the total relationship between "front entrance" features and physical functioning was attributable to their direct relationship with physical functioning.
Besides assessing the regenerative and proliferative potentials of SCs, we also investigated functional cellular markers attributable to mitochondrial function.
The Stroop test assesses an executive function largely attributable to frontal lobe function, namely the ability to view complex visual stimuli and to direct attention and respond to one attribute while inhibiting the response to another attribute.
An additional analysis showed that the variance in fluid intelligence that was attributable to processing speed was not fully shared with the variance attributable to frontal function.
In addition, it has been noted that site pairs identified as correlated tend to be relatively close in protein tertiary structure, however, many authors have proved that correlations between sites that are physically distant in protein structures might also be attributable to protein function [16], [31], [60] [62].
There is a possibility that memory disorders might be contaminated by other disorders attributable to executive function including attention.
This effect seems to be attributable to increased function of the GABAA receptors, although increased GABA release also could play a role.
Selective constraint attributable to this function would be reflected in the strong purifying selection we observe acting on key splice sequences and would contribute to a greater retention of introns in essential genes (fig. 5).
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