Destruction of the architectural and subsequently the functional integrity of the lung following pulmonary viral infections is attributable to both the extent of pathogen replication and to the host-generated inflammation associated with the recruitment of immune responses.
The late changes in the expression of genes such as Stat1, Cxcl10, gp49b and Col5a1 may be attributable to the relatively small extent of changes in gene expression at the earlier time-points, and it is possible that early changes occurred but were not detectable in our system.
They also point out that the success of American business is to a large extent attributable to the government's support.
These advances are, to a large extent, attributable to the addition of proteasome inhibitors and immunomodulatory drugs to the armamentarium of treatment options.
Some of the differences in perspective between Sonke staff and participants and Khululeka members are to an extent attributable to the different social, educational, and economic strata they represent.
The differences may also be attributable to the different methodology used at some extent.
The methodological quality of qualitative studies could also be improved by using appropriate analysis methods, multiple coders, and describing the extent of potential bias attributable to the researcher [ 37].
Possible limitations of the study relate to the categorisation of diseases, the possible bias in patient classification, the selection of therapeutic groups, the extent of operating costs attributable to the information system, the potential impact of disease under-reporting, the variability of professional practice and information biases related with retrospective observational data.
Mean values and standard deviations of the two scales were derived to illustrate the crude extent of variation attributable to the level of neck pain.
Genetic deficits in KCC2, or its orthologs, result in increased excitability in organisms as diverse as Caenorhabditis elegans, Drosophila, and mice, 45 but it is unclear to what extent this is attributable to the structural versus transport roles of KCC2.
