These results suggest that the observed phenotypes are attributable to the deletions and not to linked mutations.
However, the diversity was mostly attributable to the entire deletion of exon 2 or exon 3 or to variations in the length of the neck region (exon 4) of DC-SIGNR.
Molecular complementation verified that the asl1 mutant phenotype is attributable to the 2-bp deletion in ASL1 encoding PRPS20, a protein belonging to the PRP family.
Closer study, in a search for an altered phenotype attributable to the ceh-63 tm541) ceh-63 tm541s guideletionhe gene's expression pattern.
This is likely attributable to the accumulation, upon Cul-4a deletion, of both DDB2 and XPC DNA-damage sensors, as well as the p21 damage checkpoint effector, leading to an enhanced activity of the global genomic repair pathway and reinforced UV-responsive G1 DNA-damage checkpoint.
Additionally, she has developed insulin-dependent diabetes mellitus and euthyroid goiters potentially also attributable to the large cumulative burden of deletions.
Together, our data support the notion that the beneficial effects of ROCK1 deletion are partially attributable to the reduced actomyosin contraction via inhibition of MLC2 phosphorylation.
This recovery was not attributable to the accumulation of suppressor mutations because conidia from the deletion strain exhibited the severe growth phenotype of the original transformant at both temperatures (data not shown).
This group provided evidence that RNA molecules encoded in the region may have tumour suppressor activity, but it is also probable that the high frequency of deletions may in part be attributable to the instability of the region.
The replication of Salmonella lacking PagJ or PagK1 only was equivalent to that of wild-type bacteria, raising the possibility that the attenuated survival of the triple deletion strain (pagJ/ pagK1/ pagK2) was likely attributable to the loss of PagK2.
We first compared global Tup1p occupancy data with the transcription profile of a tup1 deletion strain to examine the correlation between Tup1p promoter occupancy and gene repression attributable to the TUP1 gene [23,24].
