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Tear formation is, in part, attributable to the accumulation of subrupture tendon fatigue damage.
The transient behavior is attributable to the accumulation of Branched rather than IEC.
A dysfunctional heat shock response logically triggers UPR of the ER attributable to the accumulation of misfolded proteins.
This recovery was not attributable to the accumulation of suppressor mutations because conidia from the deletion strain exhibited the severe growth phenotype of the original transformant at both temperatures (data not shown).
Since this persistence or 'legacy' effect, cannot be attributable to the accumulation of enclomiphene citrate, which is known to have a serum half-life of ∼7 h [ 26], we believe that it may be the effect of the anti-hormone on a third factor, perhaps on one or more elements of the hypothalamic-pituitary-gonadal axis.
Some of the side effects observed at the higher doses, in particular the fatigue, diarrhoea, alopecia and vomiting are perhaps attributable to the accumulation of the inorganic metabolite selenite, a selenium compound with marked cytotoxic properties and a very different pharmacokinetic profile compared with selenate, as confirmed in this study (Lu et al, 2009).
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This is likely attributable to the accumulation, upon Cul-4a deletion, of both DDB2 and XPC DNA-damage sensors, as well as the p21 damage checkpoint effector, leading to an enhanced activity of the global genomic repair pathway and reinforced UV-responsive G1 DNA-damage checkpoint.
Drug resistance was attributable to the decreased accumulation of drugs within cancer cells because of increased drug efflux.
Speculatively, this trend may be attributable to the preferential accumulation of aluminum due to the biochemistry of tumorous tissues, as previously hypothesized by Mannello [ 21].
Some of this size diversity is also attributable to the differential accumulation of plasmids and prophages.
During routine propagation of esl1 Δ esl2 Δ double mutants, we noticed that culture plates had an increased incidence of white colonies, which is often attributable to the spontaneous accumulation of mitochondrial DNA mutations (Zhao et al. 1998).
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