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Linkage map results were carefully curated manually to correct for results attributable to genotyping error and to resolve ambiguities.
The deviation from Hardy Weinberg equilibrium was attributable to genotyping error, as we found 42 (57.53%) of the heterozygote controls and 19 (54.29%) of the heterozygote patients falsely classified as His113 homozygotes (data not shown).
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Barley is a selfing species and progeny from breeding crosses were genotyped at the F4 6 generation, so SNPs or samples with elevated heterozygosity are likely attributable to genotyping errors.
The 2.5% of single mismatches in the families studied were attributed mostly to genotyping errors and to a lesser extent to null alleles.
50 Fourth, missingness of genotype information can occur by chance, due to genotyping errors or clinical ascertainment.
In certain occasions the dinucleotide repeats based allelic variation results in shadow bands or stutter bands during electrophoresis thus leading to genotyping errors (Hoffman and Amos [2005]).
The Hardy-Weinberg equilibrium was violated in the general population, and this could have been due to genotyping errors, as RFLP-PCR data is sometimes difficult to interpret.
This suggests that, rather than having a population genetic explanation, this departure is likely due to genotyping errors.
Linear models were used to detect potential false positives due to genotyping errors.
hsphase was more robust to genotyping errors than PedPhase 3, AlphaPhase and BEAGLE.
It produces consistent results across a broad range of parameter choices and is insensitive to genotyping errors and noncrossover products.
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