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The heterogeneity between the outcomes observed in different studies may be attributable to effect modification by genetic factors, for example polymorphisms of the CYP1A2 genotype, an enzyme involved in the metabolism of caffeine (Goodman et al, 2003).
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United's immediate task is to cut costs but it also faces problems on its revenue side, some, but not all of which, are industrywide and attributable to effects from Sept. 11.
The majority of the cholesterol-independent or pleiotropic effects are attributable to effects on endothelial function and, specifically, increases in the bioavailability of endothelium-derived NO [ 5– 7].
Thus, the effects of N1-ICD overexpression and SOX2 knockdown on sphere formation were not merely attributable to effects on cell proliferation.
The AC dinucleotide bias in this model is mainly attributable to effects seen in a dimer TR model [see Additional file 4].
Therefore, the direct antioxidant effects of resveratrol are likely to play only a secondary role in vasoprotection, and the protective properties of resveratrol are more likely to be attributable to effects on pro- and antioxidatives gene products.
Only l(3) L6332 showed a significant increase in tau expression but suppressed toxicity; thus, its modifying effect is not attributable to any effect on tau expression.
This implies that the protective effect of statins is not solely attributable to the effect on these cardiovascular risk factors.
This result may be attributable to an effect of genistein on a general or unspecified pathway in the early embryonic stage rather than on differentiated functions.
Investigation is ongoing to determine the extent to which the observed decreases may be attributable to vaccine effect and to further quantify vaccine effectiveness on type-specific lesions.
All these effects were attributable to paracrine effects of the injected cells, since we could find no evidence of the labeled cells differentiating into cardiomyocytes.
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