One reason for the variation in attributable fraction in addition to different levels of exposure to radon may be differences in smoking habits.
In some previous reports of genetic association, effect sizes have been quantitated as a population-attributable risk in addition to the odds ratio.
The DAC6-specific inhibitor tubacin [1] has been reported to have multiple effects on lymphoid cells attributable to DAC6 inhibition in addition to inducing acetylation of tubulin and HSP90.
As mothers transmit genes to their offspring, the link between maternal smoking and offspring outcomes could be attributable to inherited effects, in addition to any true environmentally mediated effect (e.g., the effects of cigarette toxins).
Indeed, we can ponder that the incurability of stage IV disease could be attributable to accelerated genetic chaos in addition to the rate of growth and overall burden of disease.
Perhaps these differences are attributable to important Opa1 functions in addition to mediating inner mitochondrial membrane fusion, such as being a critical modulator of cristae architecture (and therefore of respiratory complex functioning) (Frezza et al, 2006; Cogliati et al, 2013).
Thus, the observed mean weight loss in obese persons may be partially attributable to changes in self-reporting in addition to real weight changes.
In 2005, the Early Breast Cancer Trialists Collaborative Groupp (EBCTCG) showed that anthracycline-containing regimens account for up to a 38% (postmenopausal) and 20% (premenopausal) relative reduction in the cumulative 15-year mortality in addition to that attributable to endocrine therapy [ 26].
Furthermore, varying levels of uric acid in human populations, in addition to being attributable to dietary habits, are likely the result of evolutionary mutations that took place greater than 8 million years ago [ 13, 14].
Ascertaining accurate background rates of events in any population is difficult [11, 18, 19] and we acknowledge that this study is unable to inform on excess risk attributable to use of the vaccine, in addition to those risks likely as a result of complex morbidities seen in target vaccination groups, particularly since the number of unexposed participants was low.
