The precise role and long term attributable benefit of this technique requires confirmation.
The attributable benefit DrotAA may have once had on mortality could have been lost because of improved overall sepsis care.
In this situation, upstream approaches (e.g., larviciding, personal protection) discount the attributable benefit of downstream interventions (e.g., adulticiding).
It is conceivable that the preexisting and/or newly developing frailty modifies the potential attributable benefit of timely and effective acute physiologic support in the critically ill patient.
Retrospective analysis of data from these pivotal trials suggests that attributable benefit of herceptin is greater in those patients who express HER-2 at the highest levels, that is 3+ expression by immunohistochemistry.
The major difficulties in interpreting these studies is that they are retrospective analyses and, in many instances, there is no satisfactory 'control' arm against which to test attributable benefit of a treatment intervention in different HER-2 subgroups.
Data from randomized controlled trials show significant population-attributable benefits of treated bed nets among populations exposed to moderate to high levels of stable Plasmodium falciparum transmission, i.e., where infection prevalence is ≥ 5%.
Elaborate and test a method to extrapolate the population attributable fraction (benefit of an intervention to reduce the exposure of a given population to a given risk factor) to another population allowing for effects of synergistic factors.
However, the cisplatin-attributable survival benefit is small and toxicity substantial.
This paper describes benefits attributable to state-level energy efficiency programs.
