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The low risk of hypoglycemia and good tolerability of the DPP-4 inhibitors (21– 23) make them attractive considerations for use in hospitalized patients.
The low risk of hypoglycemia and good tolerability of dipeptidyl peptidase 4 (DPP-4) inhibitors however make them attractive considerations for use in hospitalized patients.
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Finally, heat transfer between fluid and solid regions is enhanced with helical fins, which may be an attractive consideration in future designs to enhance performance and/or safety.
These attributes make APC an attractive consideration for clinical conditions associated with increased microvascular permeability in general, including ALI, irrespective of the presence of sepsis.
Furthermore, its endogenous nature, lack of systemic side effects, ability to bind selectively and inactivate TGF-β, and its demonstrated anti-fibrotic effect in other organ systems, makes it an attractive consideration.
The lower cost of BTE, as compared to pure theaflavins, make it attractive for consideration as a safe and effective as an antiviral agent.
In all these cases, antibody-mediated pharmacodelivery options are particularly attractive in consideration of the fact that most conventional cytotoxic agents and many therapeutic proteins exhibit a reduced uptake at the tumour site, compared to normal organs (Bosslet et al, 1998; Tarli et al, 1999).
While not as theoretically efficient as active gene drive mechanisms, the MLA approach has several advantages that make it a potentially attractive strategy for consideration.
In addition to the flexibility to handle different types of traits, other attractive generalizations include consideration of multiple loci simultaneously.
FACT typically has much higher caseloads than ACT, making it an attractive alternative for consideration for both high and moderate needs participants.
Bicycle helmet legislation has not been universally implemented in the developed world as yet, and yet a cost effectiveness of $170/DALY (discounted at 3%) makes them attractive for further consideration.
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