The phrase "attenuation of virus" is correct and usable in written English.
It can be used in scientific or medical contexts when discussing the reduction of the virulence or infectiousness of a virus.
Example: "The researchers focused on the attenuation of the virus to develop a safer vaccine."
Alternatives: "reduction of virus" or "diminution of virus".
We found that a combination of transcriptional (promoter) and post-transcriptional (miRT) targeting is clearly advantageous in terms of attenuation of virus replication in hepatic cells.
Again, although there was a suggestion of attenuation of virus replication (i.e. larger tumors), dexamethasone had no significant effect on therapeutic efficacy of analyzed viruses (P = from 0.8897 to 0.9441).
Attenuation of virus replication in the lung and latent virus load in the spleen may be related to EGFP expression although the sEGFP7 line is on a C57Bl/6 background and EGFP has been reported to have a minimal immunogenic effect in this mouse strain [36].
As documented in other studies (Burns et al., 2009; Atkinson et al., 2014), these dinucleotide frequencies may contribute additionally to the observed attenuation of virus replication.
This distinct mode of inhibition may be exploited in vivo for siRNA-mediated attenuation of virus release and, consequently, virus spread.
Wesselsbron is a mosquito-borne flavivirus initially thought to cause outbreaks analogous to RVF, and vaccine was produced by similar empirical attenuation of virus by intracranial passage in mice (33, 35 ).
Several strategies to produce live attenuated tetravalent vaccines are being pursued including attenuation of viruses by conventional passage in tissue culture or introduction of defined attenuating mutations into recombinant DEN viruses [ 6- 9].
Synthetic attenuated virus engineering (SAVE) is an emerging technology that enables rapid attenuation of viruses.
Important, that the method of attenuation of viruses by deleting interferon antagonist must be suitable for different age groups of people and people having innate immune deficiencies.
Based on these data sources, an estimate of 2-log is used in the model as the mean attenuation of viruses during 15 days of anaerobic digestion in each of the risk assessment models.
Reviewer #1 1) That CpG and UpA dinucleotide frequency correlates with attenuation of viruses, rather than 'codon pair bias' or 'codon de-optimization', is a feature of these approaches rather than an artifact, in this reviewer's opinion.
