Sentence examples for attenuating the release from inspiring English sources

Thus, preclinical and clinical evidence suggests that BoNTA, recently introduced for the treatment of chronic migraine and medication overuse headache [66 68], may exert its beneficial effect by decreasing mechanical sensitivity of cranial muscle nociceptors through inhibition of glutamate release and by attenuating the release of CGRP from muscle nociceptors.

Alternatively, Akt may act at the mitochondria, directly attenuating the release of pro-apoptotic proteins from the mitochondria to the cytoplasm.

Since leukocytes were, therefore, thought to be of central importance in the development of organ injury, the authors hypothesized that APC inhibits neutrophil adhesion, thereby attenuating the release of neutrophil elastase and oxygen radicals, both of which increase vascular permeability.

RC-3095, a selective GRPR antagonist, has been shown to have anti-inflammatory properties in murine models of arthritis, gastritis, uveitis, and sepsis by attenuating the release of proinflammatory cytokines such as tumor necrosis factor-alpha (TNF- α) and interleukin-1-beta (IL-1 β) and the activation and migration of mononuclear cells to sites of inflammation [ 15].

Firstly, triptans attenuated the release of vasoactive peptides trigeminal system, as well as reduced the migraine vascular inflammation.

Midazolam attenuates the release of catecholamines in vivo and induces vasoplegia, which contributes to the resulting haemodynamic changes [7, 8].

DA neurons derived from HLA-G1-H1 hES attenuated the release of proinflammatory cytokines IL-1β and IFN-γ from lipopolysaccharide (LPS -stimulated BV2 microgLPS -stimulated

Additionally, decreased mitochondrial activity may attenuate the release of apoptogenic factors [22], [35].

K+ efflux through voltage-gated K+ (Kv) channels can attenuate the release of neurotransmitters, neuropeptides and hormones by hyperpolarizing the membrane potential and attenuating Ca2+ influx.

Adenosine attenuates the release of catecholamines, β-adrenoceptor-mediated myocardial hypercontraction, and calcium overload via A1 receptors.

FGF8 induced the production of proMMP-3 by cultured chondrocytes, and anti-FGF8 antibody attenuated the release of these factors.