Structural constraint is an effective approach which can attenuate the migration artifacts while preserving the information of subsurface structures.
When MG-63 cells were simultaneously transfected with pre-miR-29b and the CDK6 overexpression plasmid, CDK6 dramatically attenuated the migration suppression by miR-29b (Fig. 5C).
1,10 phenanthroline was able to significantly attenuate the migration and invasion of thyroid cells.
Pretreating OECs with this pharmacological inhibitor blocked the activation of ERK1/2 and greatly attenuated the migration of these cells induced by reactive astrocyte-conditioned medium, glial scar tissue, or recombinant TNF-α.
Conditioned medium from PCs under high glucose conditions attenuated the migration of retinal ECs.
These results indicated that sub-cytotoxic MJ attenuated the migration, invasion and angiogenesis of gastric cancer cells in vitro.
Here, we found that GLA attenuates the migration and invasion of breast cancer cells by inhibition of the EMT.
In scratch migration assay, sub-cytotoxic MJ attenuated the migration capabilities of SGC-7901 and MKN-45 cells in a dose- and time-dependent manner.
Furthermore, AN3CA/exFOXA1 cells exhibited a high migration rate as compared with AN3CA/NC cells, but cotransfection with siAR (AN3CA/exFOXA1 + siAR) did not significantly attenuate the migration rate.
Treatment of MSCs with PI3K-specific inhibitor (LY294002) and MAPK inhibitor (PD98059) significantly attenuated the migration of the CXCR4-MSCs [ 98].
Restoring expression of ET-2 and ET-3 in human cells significantly attenuated the migration and invasion of human colon cancer cells (Wang et al., 2013).
