Sentence examples for attenuating the efficacy from inspiring English sources

Though antioxidant vitamins such as retinoids, vitamin C, vitamin E and carotenoids have been extensively investigated in cancer prevention, the role of these vitamins in attenuating the efficacy of chemotherapeutic agents needs to be elucidated.

The axonal amplification to somatic spikes would be a case, if the inhibition of spikes' propagation in presynaptic axons attenuates the efficacy of synaptic transmission or if the incomplete somatic spikes become bigger in the axons.

Although blood pressure lowering effects of sEH inhibition depend on their vasodilative and natriuretic effects, it is also possible that the renal dysfunction after 5/6-Nx [29] attenuates the efficacy of sEH inhibition on blood pressure.

SirT1 deficiency alters the homeostasis of gene expression and attenuates the efficacy of IGF-1 signaling.

However, due to the complexity of the human body, some substances in the circulation may attenuate the efficacy of paclitaxel.

A number of mechanisms have been reported to produce MDR, including altered activity of specific enzyme systems such as glutathione S-transferase (GST) and topoisomerase, which can attenuate the efficacy of anticancer drugs [ 18, 19].

We found that knocking down of Bad attenuates the cytotoxic efficacy of sorafenib.

This finding is further substantiated by the result that EEF2K silencing significantly attenuated the antitumor efficacy of oxaliplatin against colon cancer cells (Fig. 3J).

RhoA activation is associated with entry and exocytosis of viruses, and LPA might synergize with these events and also attenuate the antiviral efficacy of macrolide antibiotics.

Considering these points, the development of a drug delivery system is becoming increasingly important in the treatment of vitreoretinal diseases by facilitating the drug efficacy and attenuating the adverse effects whilst assisting their interaction with ocular tissues (Wong et al. 1987).

ICS is effective in allergic asthma 15, and this study establishes the efficacy of FF in attenuating the EAR, LAR, and AHR in allergic asthma patients.