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Similarly, deletion of either iglC or FTT0918 attenuates growth of Schu S4 in macrophages and/or in mice [12].
These GEP observations support the findings that PTH promotes bone anabolism, does not increase osteoclast activity, and attenuates growth of myeloma cells in bone.
Results clearly indicate that AT2 receptor over-expression significantly attenuates growth of co-cultured PAN02 cells.
In support of this, the cort-HFD-treated animals in this study showed a significant reduction in epitrochlearis (primarily composed of type II fibers) but not in soleus (primarily type I) muscle mass, suggesting that this treatment attenuates growth primarily in glycolytic muscle fibers.
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In contrast, some large-bodied species likely have what is known as indeterminate, or attenuated, growth.
If there is a slippery slope here, the much more widespread use of drugs in "problem" children who are diagnosed as having attention deficit hyperactivity disorder poses a far greater risk than attenuating growth in a small number of profoundly disabled children.
However, AM2-S31N/L26I/A30T viruses displayed attenuated growth as well as inability to compete with AM2-S31N viruses.
Upon small interfering RNA-mediated silencing of endogenously expressed UCH-L1, a similar hyperubiquitinylation phenotype, reduced ErbB1/2 content, and attenuated growth was observed.
Un-engineered human and rat umbilical cord matrix stem cells (UCMSCs) attenuate growth of several types of tumors in mice and rats.
Smad7, the negative regulator of TGFβ signaling, inhibits both NF-κB and TGFβ activation and thus plays a pivotal role in the prevention and treatment of oral mucositis by attenuating growth inhibition, apoptosis, and inflammation while promoting epithelial migration.
PMA also significantly attenuated growth of both MCF-7 and BT-474 cells in a concentration-dependent manner with an inhibition of 77.8% ± 12.4% and 50.6% ± 3.7%, respectively, at 10 ng/mL PMA (Fig. 1C).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com