Sentence examples for attenuated the interaction of from inspiring English sources

De-conjugation of SUMO2/3 by SENP3 attenuated the interaction of Sp1 with RNF4.

Deletion of the CL4-binding region (C-CPE303) attenuated the interaction of C-CPE with CL4-BV (Fig. 1C).

Further co-IP experiments proved that overexpression of KSR1 attenuates the interaction of SIRT1 DBC1, which therefore allows SIRT1 to interact more with p53 resulting in decreased p53 acetylation.

Specifically, SMYD2-mediated monomethylation of p53 K370 attenuates the interaction of p53 with p53 target promoters and consequently antagonizes p53-dependent transcriptional regulation [ 112].

It was thought to exert its effect through decreasing the viability of T helper type 1 cells and attenuating the interaction of T cells with macrophages.

Reciprocally, changes to gene expression by sAPPα via the activation of NF-κβ may attenuate the interactions of Aβ [ 77] and this can be understood as reciprocal indirect feedback from the α-pathway on the β-pathway.

Both chemicals attenuated the interaction between p50 and Annexin A2-WT, which was either endogenous or myc-tagged exogenous.

In the present study, we demonstrated that phosphorylation of FE65 Ser by SGK1 attenuates the interaction between FE65 and APP.

Phosphorylation of p53 at Ser promotes p53 stabilization by attenuating the interaction between p53 and its negative regulator MDM2.

Our preliminary evidence shows that transfection with constitutively active Akt1 reversed the loss of MDM2 phosphorylation in the presence of I3C, prevented the observed apoptotic response and attenuated the I3C-induced interaction of MDM2 with nucleostemin.

Clozapine, but not haloperidol, significantly attenuated the decreased social interaction behavior of HB-EGF KO mice (P<0.05 vs. vehicle-treated HB-EGF KO mice) (Fig. 2d).