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Acutely after trauma, blood neutrophil genome-wide expression analysis revealed an attenuated transcriptomic response as compared to the young; this attenuated response was supported by the patients' plasma cytokine and chemokine concentrations.
This suggests a developmental maturation of the TLR response instead of an attenuated response due to infection.
The apparently attenuated response to α1-adrenergic agonists in vivo may reflect diminished response to these normally synergistic vasopressor pathways.
Nine of these patients (13.8%) were unresponsive and nine patients (13.8%) had attenuated response to second lithium treatment.
Lastly, attenuated response scales such as the 5-point Likert scale can be problematic as they may be subject to floor and ceiling effects (Harris and Hahn 2011).
In addition to an attenuated response to lifestyle programs, AA women also demonstrate high rates of obesity, diabetes, and cardiovascular disease.
Furthermore, this polymorphism tends to show an attenuated response to an HMG-CoA reductase inhibitor in terms of the cholesterol lowering effect.
Also, an attenuated response of urinary NGAL was found in adult cardiac surgery patients in whom a lower incidence of AKI was noted when sodium bicarbonate was administered instead of sodium chloride [34].
AML-MLL tumor cells are resistant to current genotoxic therapies because of an attenuated response by p53, a protein that induces cell cycle arrest and apoptosis in response to DNA damage.
Task performance (low error and bias) was related to attenuated response in ambiguous conditions while increased response in regions associated with the default mode network was associated with greater overall error and bias towards other.
A detailed transcriptomic analysis of roots of transgenic plants subjected to revitalization after drought stress revealed attenuated response through the HvHK3 cytokinin receptor and up-regulation of two transcription factors implicated in stress responses and abscisic acid sensitivity.
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