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It has been suggested that exercise training results in compensatory mechanisms that attenuate weight loss.
We confirmed the findings of previous studies that a relatively high dose of exercise (12 KKW or 194 minutes per week) results in compensatory mechanisms that attenuate weight loss in previously sedentary women.
Finally, reduced alcohol consumption in early adulthood can help to attenuate weight gain and abdominal obesity in adulthood (60).
In discussion, the question was raised as to how a reduction in physical activity might help attenuate weight loss in cancer cachexia patients, since a reduction in physical activity would result in reduced lean body mass (LBM).
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This corresponded with attenuated weight gain and adiposity.
SY given in combination with EtOH appeared to prevent the EtOH-associated low birth weight and attenuated weight gain.
Conditional deletion of ALK7 in adipose tissue attenuates weight gain and fat deposition under a high fat diet.
In vivo studies showed that neither the D- nor the -peptides significantly attenuated weight loss, although the -peptide did show a tendency to increase lean body mass.
6 Among male participants 40 75 years of age in the Health Professionals Follow-up Study, increasing vigorous exercise to 1.5 hours/week attenuated weight gain but was insufficient to offset it completely.
Bypassing the deficiency in the 15-LOX enzyme, exogenous administration of PD1-isomer to eosinophil-deficient mice following colonic injury markedly attenuated weight loss, colon shortening, histological indices of injury and inflammation, PMN infiltration and proinflammatory cytokine production including TNF-α, IL-1β, IL-6 and inducible nitric oxide.
Antisera reactive to a 19mer corresponding to the N-terminal amino acids of the PIF receptor was effective in attenuating weight loss in mice bearing the cachexia-inducing MAC16 tumour, through an increase in lean body mass, attributed to an increase in protein synthesis and decrease in degradation in skeletal muscle.
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