Sentence examples for attenuate the repression from inspiring English sources

Deletion of fnr would lower PFL activity and attenuate the repression of PDH, the result being the production of NADH instead of formate when pyruvate is converted to acetyl-CoA.

Our data extend these findings to show that under conditions of differentiation in the absence of LIF and addition of RA, loss of Pten and increased phosphorylation of Akt attenuate the repression of Nanog and Oct4 mRNA as previously reported, but only in the emerging ECC population and not in the general differentiated population.

In addition, the ROCK inhibitor attenuated the repression of NRXN1/2/3α splicingining in the hippocampus in the conditioned significantly compared to non-conditioned animals (Figure 6 panels A, B and C).

Interestingly, depletion of the corepressor DP97 attenuated the repression of ErbB2 [ 5].

In comparison, the intact miR-92 significantly attenuated the repression of c-Myc-induced apoptosis by mir-17-92 mir-17-92 mir-17-92

We found that Bmh2, but not Bmh1, attenuates the repression of all of these genes following rapamycin treatment.

BMH2, but not BMH1, attenuates the repression of genes involved in some functions required for ribosome biogenesis.

To further demonstrate that TSC2 regulates intestinal cell differentiation through Notch signaling, we next determined whether inhibition of Notch with DBZ attenuates the repression of intestinal cell differentiation induced by TSC2 inactivation in the intestine.

Mutation of E-box B or E-box C but not A significantly attenuated the repression of the reporter gene activity by Id2-DBM-δHLH, which suggests that the E-box-binding transcription repressors are involved in HLH domain-independent Id2 repression of E-cadherin transactivation.

Because we previously showed that REDD1/TSC2/mTOR signaling pathway regulates the expression of MUC2 in intestinal cell lines, we next determined whether the inhibition of mTOR with rapamycin attenuates the repression of goblet and Paneth cell differentiation induced by TSC2 inactivation in the intestine.

Moreover, when treating the cells with DNA methyltransferase inhibitor which attenuates the global repression of DNA methylation, reprogramming efficiency accelerates a lot, about 1.1% in 20 cell cycles (see Additional file 1 and Fig S2(b)).