Sentence examples for attenuate the local from inspiring English sources

LysoSensor™ Yellow/Blue dextran (Life Technologies Corporation, Grand Island, NY, USA) was loaded into the dextran nanoparticle to evaluate the ability to attenuate the local acidic microenvironment in the PLGA microsphere during the in vitro release period.

The positive charges can attenuate the local K+ concentration at the entrance of the extracellular vestibule through an electrostatic mechanism [21], [22].

One way to verify this interpretation is to attenuate the local bias given by homogeneous stress items, by presenting prime stimuli with mixed stress pattern types.

These results may reflect an initial but failed attempt to attenuate the local inflammation caused by endometrial fragments in the pelvic cavity.

The anti-inflammatory and immunomodulating properties of IVIG may attenuate the local immune activation on both the cellular and the humoral level [ 16].

Acetylcholine interacts with the α7-nicotinic acetylcholine receptor (α7nAChR) that is expressed in macrophages and other cells and inhibits the production of proinflammatory cytokines to attenuate the local and systemic inflammatory responses [ 7, 8].

Among these drugs, ketotifen fumarate, attenuated the local allergic reaction in patients with AC [ 20, 21] and the efficacy and safety of this drug in AC management has also been shown in human conjunctival allergen challenge model [ 44, 45].

The lack of properdin, however, attenuates the local generation of C5a and IL-6 in synovial fluid and alters IFN-γ production, IFN-γ receptor expression, and signal transducer and activator of transcription (STAT 1 signaling in ZIA splenocytes.

We have demonstrated that DHEA attenuates the local regeneration of glucocorticoids in adipocytes and have shown this is via two concerted mechanisms: attenuation of the induction of 11β-HSD1 differentiationtiandon and inhibition of expression of H6PDH, the enzyme that regenerates the cofactor NADPH that is required for 11β-HSD1 oxoreductactivityvity (25).

The protocols developed here will allow us to explore in detail the processes responsible, and when these are identified it may be possible in the future to attenuate the ventilation-induced exacerbation of local and systemic inflammation while retaining immune responses to infection intact.

The final target learner uses the supervised local weights to attenuate the effects of negative transfer.