Sentence examples similar to attenuate the differentiation from inspiring English sources

Our results indicate that the defects in Prdm14 mutant cells arise from a lack of repression of the DNA methyltransferase machinery, and by a failure to attenuate the differentiation-inducing FGF signalling pathway.

It would therefore appear that NOX1-induced ROS accumulation attenuates the differentiation capacity of aASCs.

Huleihel L et al. confirmed that let-7d significantly attenuated the differentiation of fibroblasts into pathological myofibroblasts by targeting HMGA2.

These results demonstrate that apelin attenuates the osteoblastic differentiation of AVICs via the ERK and PI3-K/Akt pathway.

These results indicated that exenatide treatment and RANKL siRNA attenuated the osteoblastic differentiation and calcification of human CVSMCs.

In fact, the challenge of development appears to be to control and attenuate the growth potential to enable functional differentiation.

IL-10 has also been reported to promote the differentiation of M2 macrophages and attenuate the M1 macrophage population (30).

This data strongly supports our previous findings, which suggested that LIF recruitment in cell culture might be attenuating the terminal cell differentiation in order to maintain the pool of neural stem cells.

It is entirely feasible, however, that Wnts also increased osteoblast number by attenuating the apoptosis, stimulating the differentiation, or increasing the proliferation of the progeny of CFU-OB, or a combination of these mechanisms.

These data demonstrated that Klotho may attenuate osteoblastic differentiation and the calcification of VSMCs by inhibiting the Wnt/ β-catenin signaling pathway.

To further demonstrate that TSC2 regulates intestinal cell differentiation through Notch signaling, we next determined whether inhibition of Notch with DBZ attenuates the repression of intestinal cell differentiation induced by TSC2 inactivation in the intestine.