Sentence examples for attenuate the activity from inspiring English sources

Because DUSP4/6 and SPRY4 are negative regulators for ERK1/2 and RTK, respectively [31, 61, 110], these observations may suggest that ETS1 is required for robust RAS/ERK pathway activation, and reducing its activity would attenuate the activity of ERK1 and ERK2.

Repetitive transcranial magnetic stimulation is increasingly used as a therapeutic tool in psychiatry and has been demonstrated to attenuate the activity of the stress hormone system.

In the primary feedback loop, PER and CRY assemble into repressor complexes next attenuate the activity of CLOCK BMAL1.

Nevertheless, in oxidative stress conditions, ERK1/2 might adopt a pro-apoptotic role since they attenuate the activity of protein kinase B (PKB, EC 2.7.11.1), called also AKT1 [159].

Studies suggest that ERβ can attenuate the activity of ERα, potentially through heterodimerization [ 14, 16].

Thus, carnosine could be a promising anticancer drug through its ability to attenuate the activity of CA IX.

Proteinaceous peptidase inhibitors are proteins that have the potential to attenuate the activities of peptidases by the formation of complexes with the enzymes.

We identify the auxin-dependent transcription factor ARF5/MONOPTEROS to cell-autonomously restrict the number of stem cells by directly attenuating the activity of the stem cell-promoting WOX4 gene.

However, the results of Go's study is exactly contrary to ours which indicated that pre-treatment with VPA significantly attenuated the activity of NF-кB pathways and led to the protective effect on nervous system.

Our present study also showed that the ERK inhibitor, PD98059, attenuated the activity of ALP that had been decreased by apelin.

However HIF1, SP1, and SRE had decreased activity relative to untreated cells only at 24 h, suggesting that E2 attenuated the activity of these factors at the early stages of culture.