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Specific inhibition of NF-κB activity has been found to attenuate loss of skeletal muscle mass in response to various catabolic stimuli including proinflammatory cytokines, tumor load, denervation, and unloading [13], [14], [15], [16].
25 It should be addressed whether attempts to attenuate loss of muscle mass during neoadjuvant CRT are effective and whether they result in decreased FTR rates.
In the present study we tested the ability of a novel tetrapeptide, EA-230, to improve survival and attenuate loss of kidney function in a clinically relevant model of sepsis – cecal ligation and puncture (CLP) in mice.
For an obese individual, the ADA recommends a modest weight loss of 5%10%% body weight, while physical activity can help attenuate loss of lean body mass that can occur with energy restriction.
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In combination with the present data, these observations suggest that Kihi-to can attenuate losses of axons, synapses and myelin in critical areas for memory recall and recognition.
Sinupret® treatment (SIN + AR) significantly attenuated loss of epithelial height due to acute rhinitis induction (p < 0.05 vs. AR) (Table 1, Fig. 1a-c).
We have demonstrated that hepatocyte growth factor (HGF) attenuates loss of both spinal and brainstem motoneurons of ALS model mice expressing mutated human SOD1G93A (G93A).
PRO significantly attenuated loss of bone mineral density (BMD) at whole body (WB) (−0.1% in PRO vs. −2.4% in VEH, P < 0.05), but not at spine or femur 4 weeks after OVX.
Based on the currently available scientific information, we propose that exercise training and probiotic treatments could delay inflammation, ameliorate oxidative stress, and decrease levels of beta amyloids, thereby attenuating loss in brain function.
Indeed, Treg transfer into MPTP-treated animals attenuated loss of nigral DA neurons [ 84, 85].
Indeed, Treg transfer into MPTP-treated animals attenuated loss of nigral DA neurons (Reynolds et al., 2010).
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