Sentence examples for attenuate initiation from inspiring English sources

Furthermore, specific low-complexity sequences or tandem repeats in the degradation initiation site can attenuate initiation or progression of degradation, thereby affecting substrate half-life (Sharipo et al., 1998; Tian et al., 2005; Zhang and Coffino, 2004).

cIAP1 protein expression is also repressed as the result of both a long (1.2 kb) 5′UTR that hinders ribosomal movement, and a small upstream open reading frame (uORF) that strongly attenuates initiation of cIAP1 translation at the authentic AUG start codon.

PERK phosphorylates eIF2α to attenuate translation initiation and thus is responsible for the NMD attenuation.

Such phenolic compounds, widely present in plants, inhibit or attenuate the initiation, progression and spread of cancer [3].

Accordingly, therapies designed to attenuate thrombus initiation and propagation, reflecting integrated platelet-mediated and coagulation protease-mediated events, respectively, represent a standard of care.

We hypothesized that local preemptive bupivacaine treatment prior to nerve injury in a rat model of spinal nerve ligation (SNL) would attenuate the initiation and/or maintenance of neuropathic pain behaviors.

We hypothesized that local treatment with bupivacaine prior to nerve injury in a rat model of spinal nerve ligation (SNL) would attenuate the initiation and/or maintenance of neuropathic pain behaviors.

Clozapine attenuated the initiation of alcohol drinking and development of alcohol preference while haloperidol did not.

In essence, a selection marker with a startcodon that confers attenuated translation initiation frequency was placed upstream of the gene of interest with a startcodon that confers optimal translation initiation.

Targeting HIFs in GSCs inhibits self-renewal, proliferation, and survival in vitro, and attenuates tumor initiation potential of GSCs in vivo.

Phosphorylated eIF2 α (p-eIF2 α) markedly attenuates translation initiation and overall protein synthesis, allowing for conservation of cellular resources.