Sentence examples for attenuate infection from inspiring English sources

However, patterns of changing CTL specificity and viral mutation in natural infection, in addition to data from macaque and in vitro studies, suggest that a more focused approach might optimize the activity of vaccine-generated CTLs to prevent or attenuate infection.

Infection does not appear to cause injury to ticks and ticks do not attenuate infection.

Strikingly, there was a large overlap in the drugs identified that attenuate infection in both cell types, indicating pathways utilized by the virus in both mammals and insects (p<10−16; Figure 2E).

Because antimicrobial exposure is the primary risk factor associated with CDI development, stewardship is expected to attenuate infection rates by reducing the overall susceptibility of hospital patients.

In agreement with that, a FO enriched diet (containing 1% FO providing 0.5 g EPA + DHA g/day, for 5 weeks prior to infection) was shown to attenuate infection-induced colitis in mouse infected with Citrobacter [ 123].

Endosome acidification inhibitors are also known to attenuate infections by many other retroviruses, indicating that these retrovirus infections occur through acidic endosomes [13], [14], [15], [16], [17], [18].

Inhibitors of endosome acidification attenuate infections by many retroviruses, including MLV, avian leukosis virus, Jaagsiekte sheep retrovirus, equine infectious anemia virus, and foamy virus [13], [14], [15], [16], [17], [18], [19], [20].

We identify a ZIKV variant that produces small plaques due to interferon (IFN -restricted vIFN -restrictedn and displays attenuated infection of endothelial cells.

While the PKC inhibitors routinely inhibited infection by at least 10-fold, RNAi modestly but significantly attenuated infection (∼2-fold).

Analysis of the inhibitors that attenuated infection in both cell types revealed that the inhibitors could be divided into 9 specific categories.

Inhibition of PKCε in human cells, Drosophila cells or adult flies significantly attenuated infection Together, these data show that RVFV MP12 infection of both the insect and mammalian host has conserved cellular requirements that are amenable to therapeutic intervention.