The phrase "attenuate gene expression" is correct and usable in written English.
It can be used in scientific or academic contexts, particularly in discussions related to genetics, molecular biology, or biochemistry.
Example: "The researchers aimed to attenuate gene expression to study the effects of reduced protein levels on cell function."
Alternatives: "reduce gene expression" or "diminish gene expression".
Moreover, NO was shown to attenuate gene expression associated with insulin resistance [ 15].
CtBP1 could interact with histone deacetylase to attenuate gene expression by targeting the promoter region [ 29].
DNA methylation within regulatory regions (i.e., promoters) of a gene has long been known to attenuate gene expression.
Functional assays, using RNAi to attenuate gene expression, provide evidence that such genes might play causal roles in enhancing lifespan.
We were asked to consider the possibility that Snail repression elements located within or near the proximal enhancer might attenuate gene expression.
Specifically, SIRT6 is recruited to the promoters of genes that have been activated by the NF-κB transcription factor, deacetylates H3K9 at these promoters to attenuate gene expression, and thereby limits NF-κB signaling.
In mutant cells, chromatin accessibility of periodic genes, including TORC1-responsive genes, is relatively static, concomitant with severely attenuated gene expression.
Tension improved cell viability, and, independent of cell viability, fibrochondrogenic activity by promoting expression of collagen type 1 and aggrecan genes and attenuating gene expression of IL-6.
Clusters M3 and M4 included genes without differential expression between WT and atm before IR and displayed 251 up- and 83 downregulated genes, respectively, in WT, and invariant or severely attenuated gene expression levels in atm.
Some of these interventions have striking efficacy in preventing cardiomyopathy, extending lifespan, preventing spongiform encephalopathy [2], [3], reducing anemia [7], increasing mitochondrial enzyme activity, reducing neurodegeneration and attenuating gene expression characteristic of mitochondrially mediated spongiform encephalopathy [12], [14].
Other genes in the anthocyanin pathway also had attenuated gene expression in the OE lines.
