Sentence examples for attenuate formation of from inspiring English sources

In vivo, however, inhibition of TLR-7 alone is sufficient to attenuate formation of both anti-RNA and anti-DNA antibodies and to mitigate disease, especially at early stages; in the only published comparative study [ 9], inhibition of both TLR-7 and TLR-9 did not appear to have an enhanced effect on disease over inhibition of TLR-7 alone.

ITF2357 treatments at (C) 125 nM, (D) 250 nM or (E) 500 nM concentrations attenuated formation of myofibroblasts (Scale bar = 50 μm).

Overall, these data demonstrate that expressional down-regulation of NMMIIA dramatically attenuates formation of both nascent AJ-like junctions and TJs, whereas depletion of two other NMMII isoforms does not affect the dynamics of AJC assembly.

Through rapid kinetic assays, we demonstrate that ToMOD attenuates formation of the ToMOC ToMOH complex.

The data demonstrate that enzymatic removal of the CS chains significantly attenuated formation of lung metastases in a highly metastatic mammary cell line.

In addition, DR5 silencing attenuates formation of a RIP1/FADD/caspase-8 cellsolic cell death complex and activation of caspase-8, -3 and -9.

In this study, we show that the targeted knockdown of MMP-1 in 231-BR and 231-BR3 cells not only reduced primary tumor growth, but also significantly inhibited the invasiveness of these two brain-seeking metastatic breast cancer cells and attenuated formation of experimental brain metastases.

Furthermore, there was decreased cell viability and attenuated formations of tubes in HUVEC incubated with the conditioned mediums collected from As2O3-pre-treated cells; however, knockdown of miR-155 abolished this phenomenon (Fig. 5b,c).

Our data showed that there was decreased cell viability (Fig. S1a) and attenuated formations of tubes in HUVEC (Fig. 1c,d) incubated with the conditioned mediums collected from As2O3-pre-treated cells.

In order to confirm whether inhibition of cathepsin B could attenuate the formation of glial scar, we used cathepsin B inhibitor CA-074Me as a positive control.

Here we demonstrate that subretinal delivery of an adenovirus vector expressing a transgene for a soluble non-membrane binding form of human CD59 can attenuate the formation of laser-induced choroidal neovascularization and murine MAC formation in mice even when the region of vector delivery is distal to the site of laser induced CNV.