The phrase "attenuate disease" is correct and usable in written English.
It can be used in medical or scientific contexts to describe the process of reducing the severity or impact of a disease.
Example: "Vaccination can help to attenuate disease by boosting the immune response."
Alternatives: "reduce disease severity" or "diminish disease impact."
Depending on the nature of the mutation, a range of AO splice-correcting strategies could be exploited in an attempt to restore protein function and attenuate disease.
Heart and brain protection strategies aim to prevent or attenuate disease progression and secondary injuries by halting or at least slowing the loss of cardiomyocytes and/or neurons [111].
Recent studies in animals have promoted the idea, however, that some monocyte subsets accentuate while others attenuate disease [8].
Treatment of mice with the thrombin inhibitor hirudin, also blocks inflammation in crescentic glomerulonephritis and in addition was recently shown to attenuate disease severity in EAE [53].
While a CTL based vaccine may not prevent HIV-1 infection, it may offer the opportunity to attenuate disease from subsequent infection.
In summary, here we have demonstrated that oral MTA administration is an effective therapeutic strategy to attenuate disease progression in a relevant model of liver injury and fibrosis.
In this study we have investigated the impact of the LMP7-selective inhibitor ONX 0914 on two mouse models for MS. ONX 0914 strongly attenuated disease progression in diseased animals following immunization with autoantigen or transfer of autoreactive T cells.
Further, anti-KLK6 antibodies attenuated disease manifestations in the mouse model of multiple sclerosis.
When we engineered and tested transgenic mice overexpressing BAI1, these had fewer apoptotic cells, reduced inflammation, and attenuated disease.
This attenuated disease was associated with a decrease in the neutrophil chemoattractant CXCL1.
Taken together, we demonstrate, that a β-lactam antibiotic attenuates disease course and severity in a model of autoimmune CNS inflammation.
